DeNovo Cartilage Repair

deNovo for Cartilage replacement, University Foot and Ankle Insitute Los Angeles

One of the most vexing problems in podiatric surgery over the past few decades has been surgical cartilage repair.

 

The surgeons at University Foot and Ankle Institute are pleased to offer a revolutionary technique, DeNovo cartilage repair. This new technology has shown promise in improving short term and long term outcomes of ankle joint surgery.

 

The DeNovo graft requires only one surgery, which can be performed arthroscopically and offers remarkable regenerative powers. Patients can expect a shorter hospital stay compared to open surgery, and should be back to work in about 4-6 weeks.

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Cartilage is the thick, rubbery material that coats the ends of the bones at the joint. It enables joint mobility and protects the bone from friction caused by movement. An injury can damage the cartilage, which fractures into slivers that may “float” around the joint. The defect is what’s called an osteochondral lesion, and it can cause pain and swelling in the joint and ultimately could develop into osteoarthritis.

 

Traditional Methods to Ankle Cartilage Replacement

The traditional method to repair an osteochondral lesion involves drilling tiny holes in the joint, deep into the bone marrow. The holes stimulate the bone marrow to start generating new cartilage cells to fill in the holes and repair the lesion. This technique is known as “microfracture.”

 

The tricky part of the microfracture method is that cartilage is notorious for its inability to re-generate healthy tissue on its own. Damaged cartilage, even with a boost from bone marrow, can only grow a thin and weak scar tissue, and over time, symptoms will tend to redevelop or worsen. The problem is even more likely to return if the original lesion was particularly large or deep.

 

Another method involves borrowing a sample of cartilage from another place in the patient’s body – usually the knee – and grafting it to the ankle joint. This method can be effective, but it does have its downsides. It requires two open surgeries: one to harvest the healthy cartilage, and another six weeks later to repair the damaged cartilage. This means the patient will have two surgical sites, increasing the risk for complication and increasing the amount of time it takes to full recovery.

 

The DeNovo Cartilage Repair Technique

Cartilage repair that utilizes the patients’ own tissue is what’s known as an autograft. The DeNovo technique instead employs an allograft – that is, a graft of natural, healthy cartilage donated from a cadaver. The DeNovo technique uses cartilage from a young donor, which has a “much larger capacity for self-repair” when compared to mature cartilage, explains Dr. Bob Baravarian.

 

“The DeNovo graft requires only one surgery, which surgeons can perform arthroscopically.” Dr. Baravarian is one of the world’s leading experts on minimally-invasive podiatric surgical techniques. The allograft is secured with fibrin, a biomedical adhesive. Patients can expect a shorter hospital stay compared to open surgery, and should be back to work in about 4-6 weeks.

 

The Regenerative Advantage of DeNovo Cartilage Repair

Immature cartilage has remarkable regenerative powers. Much denser than fully mature cartilage, immature cartilage is packed with cells, which begin to multiply soon after implantation. This new technique has already demonstrated its healing potential in lesions large and small, and even in those problematic lesions that don’t respond to microfracture techniques.

Over 200,000 happy UFAI patients and growing
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    Best doctor hands down. He has helped me so much, and he actually cares about you and wants the best for you.
    Gina V.
  • CustomerSure
    I couldn't be more satisfied. My procedure went better than I anticipated and my followup care has been great.
    Randell S.
  • Yelp
    I was treated by Dr. Franson last summer after waking up to a debilitating ankle pain. I had been to several doctors in the weeks leading up to Dr. Franson's office visit with no real diagnosis or treatment. Dr. Fra...
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    Dr. Justin Franson, Suzanne and Jasmine are awesome!!
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  • Yelp
    Dr. Baravarian took care of my very painful hung nail last year and I have had no problems since then. I since recommended 3 friends to him for different problems/surgeries and they are all so thankful and happy with ...
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    I have been truly amazed with Dr Baravarian. I had a loose piece of bone at the base of my fifth metatarsal. Got an X-ray and an MRI right there in the building before having it surgically removed yesterday. Surgery w...
    James D.
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    So fortunate to have found Dr Franson. I was treated by him last year for a torn achilles tendon, and today my daughter was treated by him. She's pregnant and he was very attentive to her concerns about treatment for ...
    S.K.
  • Yelp
    I am 4 weeks post surgery now and just got my cast off today. Dr. Franson is the BEST foot specialist I have ever been to. He is extremely kind, he's caring and compassionate. He truly cares about his patients and has...
    Kathleen C.
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    Enjoyed getting the left foot bunion done so much (LOL), I went back and had the bunion on my right foot removed on Sept.28 ! This recovery has been even faster than on the left foot as we religiously (thanks to my w...
    Duane D.
  • CustomerSure
    So far everything is going well. I really like Dr. Baravarian and his staff, they did a wonderful job. They are very compassionate and professional at the same time. My family and I are very happy and thankful we fou...
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